Eton Cares
Eton Cares is a full-service patient support program created to help you and your child along the treatment journey.
Please see Indication and Important Safety Information below.
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Olive, a former INCRELEX patient, at age 18
Eton Cares Program
Your rare disease journey is personal. So is your support.
When your doctor prescribes INCRELEX®, you’re automatically enrolled in the Eton Cares Program—designed to support you and your family every step of the way.
When your doctor sends your prescription to our specialty pharmacy Anovo®, this is what you can expect:
Welcome Call from your Care Coordinator to verify prescription, offer support, and answer questions
Insurance Verification to review coverage and benefits
Financial Assistance Review to explore copay programs and other support options
Medication Delivery with instructions and product-specific information
Ongoing Pharmacy Support, including refill coordination, reminders, and 24/7 access to a pharmacist
Nurse Ambassador Support to help you and your child stay on track with treatment, answer health or medication questions, and provide regular check-ins by phone
For questions or support, please contact us at our specialty pharmacy Anovo:
Anovo Pharmacy Team:
The Pharmacy Team is always available by phone 24 hours a day, 365 days a year.
A helpful tip: We recommend saving Anovo’s phone number in your contacts so you can easily recognize important calls about your prescription, refills or insurance updates.
Looking to Connect With a Peer Who Understands?
Caring for a child with Severe Primary IGF-1 Deficiency can feel overwhelming, and it may help to talk to another caregiver who has been through a similar experience. Sign up below for Eton Connect to speak one-on-one with an IncrelexPeer caregiver and:
- Hear personal experiences from another caregiver of a child living with Severe Primary IGF-1 Deficiency who takes INCRELEX
- Talk through day-to-day challenges and practical tips for managing care
- Learn about helpful support resources and ways to connect with the community
- Ask questions and hear how another family navigated their journey
Peer conversations are intended for support and shared experiences only and do not provide medical advice.
INDICATION
INCRELEX® (mecasermin) is a prescription medicine used in children 2 years and older with short stature that have severely low levels of the hormone, insulin-like growth factor-1 (IGF-1). IGF-1 is needed for normal growth.
INCRELEX is not a substitute for growth hormone. It cannot be used for children with short stature due to low levels of growth hormone, malnutrition, when their thyroid gland doesn’t make enough thyroid hormone, or when taking anti-inflammatory steroids used to manage inflammation.
IMPORTANT SAFETY INFORMATION
Always give INCRELEX exactly as your doctor directed.
Do not take INCRELEX if you are allergic to IGF-1 or any of its other ingredients. Report any allergic reactions.
INCRELEX should be injected under the skin (subcutaneous injection). It should not be injected directly into a blood vessel.
INCRELEX should not be used after growth plates close which happens during puberty.
INCRELEX should not be used in children with cancerous tumors or a history of cancer.
Hypoglycemia (low blood sugar): INCRELEX should be administered 20 minutes before or after a meal or snack and should not be administered when the meal or snack is skipped.
Checking blood glucose levels is recommended. The dose of INCRELEX may need to be adjusted until an appropriate dose is decided by your doctor.
Intracranial Hypertension: Increased pressure in your skull may occur because of cerebrospinal fluid buildup around your brain. Therefore, your doctor may require an eye examination at the start of INCRELEX treatment and periodically during the time you are taking INCRELEX.
Lymphoid Tissue Hypertrophy: Lymphoid tissue hypertrophy is a noncancerous increase in the number of immune cells called lymphocytes. Patients should have periodic examinations with your doctor to rule out potential complications.
Slipped Capital Femoral Epiphysis: Slipped capital femoral epiphysis is a bone problem where the top of the upper leg (femur) slips apart. This may lead to a serious condition where bone tissue dies due to a lack of blood supply (osteonecrosis). Get medical help for your child right away if your child develops a limp or has hip or knee pain.
Progression of Scoliosis: Your doctor will monitor you during treatment with INCRELEX if you have a history of scoliosis.
Malignant Neoplasia: There have been reports of cancerous tumors in children who received INCRELEX. It is unknown whether there is any relationship between INCRELEX therapy and new occurrence of tumors. Tumors were mostly reported in patients with rare genetic conditions of short stature associated with a higher risk of cancer, or in patients already at risk of cancer.
The tumors were seen more frequently in patients who received INCRELEX at higher than recommended doses or at doses that produced IGF-1 levels above normal for age and sex. Your doctor will carefully monitor you during your treatment with INCRELEX for development of tumors. If cancerous tumors develop, your doctor will stop your INCRELEX treatment.
Risk of Serious Adverse Reactions in Infants due to Benzyl Alcohol Preserved Solution: Serious and fatal adverse reactions can occur in neonates and infants treated with benzyl alcohol-preserved drugs. Use of INCRELEX in infants is not recommended.
The most common adverse reactions include low blood sugar, reactions at the injection site or throughout your body, and enlarged tonsils.
You are encouraged to report negative side effects of prescription drugs by contacting Eton Pharmaceuticals, Inc. at 1-855-224-0233 or the U.S. Food and Drug Administration (FDA) at www.fda.gov/safety/medwatch or call 1-800-FDA-1088.
Please see full Prescribing Information for more information.
INDICATION
INCRELEX® (mecasermin) is a prescription medicine used in children 2 years and older with short stature that have severely low levels of the hormone, insulin-like growth factor-1 (IGF-1). IGF-1 is needed for normal growth.
INCRELEX is not a substitute for growth hormone. It cannot be used for children with short stature due to low levels of growth hormone, malnutrition, when their thyroid gland doesn’t make enough thyroid hormone, or when taking anti-inflammatory steroids used to manage inflammation.
IMPORTANT SAFETY INFORMATION
Always give INCRELEX exactly as your doctor directed.
Do not take INCRELEX if you are allergic to IGF-1 or any of its other ingredients. Report any allergic reactions.
INCRELEX should be injected under the skin (subcutaneous injection). It should not be injected directly into a blood vessel.
INCRELEX should not be used after growth plates close which happens during puberty.
INCRELEX should not be used in children with cancerous tumors or a history of cancer.
Hypoglycemia (low blood sugar): INCRELEX should be administered 20 minutes before or after a meal or snack and should not be administered when the meal or snack is skipped.
Checking blood glucose levels is recommended. The dose of INCRELEX may need to be adjusted until an appropriate dose is decided by your doctor.
Intracranial Hypertension: Increased pressure in your skull may occur because of cerebrospinal fluid buildup around your brain. Therefore, your doctor may require an eye examination at the start of INCRELEX treatment and periodically during the time you are taking INCRELEX.
Lymphoid Tissue Hypertrophy: Lymphoid tissue hypertrophy is a noncancerous increase in the number of immune cells called lymphocytes. Patients should have periodic examinations with your doctor to rule out potential complications.
Slipped Capital Femoral Epiphysis: Slipped capital femoral epiphysis is a bone problem where the top of the upper leg (femur) slips apart. This may lead to a serious condition where bone tissue dies due to a lack of blood supply (osteonecrosis). Get medical help for your child right away if your child develops a limp or has hip or knee pain.
Progression of Scoliosis: Your doctor will monitor you during treatment with INCRELEX if you have a history of scoliosis.
Malignant Neoplasia: There have been reports of cancerous tumors in children who received INCRELEX. It is unknown whether there is any relationship between INCRELEX therapy and new occurrence of tumors. Tumors were mostly reported in patients with rare genetic conditions of short stature associated with a higher risk of cancer, or in patients already at risk of cancer.
The tumors were seen more frequently in patients who received INCRELEX at higher than recommended doses or at doses that produced IGF-1 levels above normal for age and sex. Your doctor will carefully monitor you during your treatment with INCRELEX for development of tumors. If cancerous tumors develop, your doctor will stop your INCRELEX treatment.
Risk of Serious Adverse Reactions in Infants due to Benzyl Alcohol Preserved Solution: Serious and fatal adverse reactions can occur in neonates and infants treated with benzyl alcohol-preserved drugs. Use of INCRELEX in infants is not recommended.
The most common adverse reactions include low blood sugar, reactions at the injection site or throughout your body, and enlarged tonsils.
You are encouraged to report negative side effects of prescription drugs by contacting Eton Pharmaceuticals, Inc. at 1-855-224-0233 or the U.S. Food and Drug Administration (FDA) at www.fda.gov/safety/medwatch or call 1-800-FDA-1088.
Please see full Prescribing Information for more information.